(3ø*(1(7ø. 1 Ders Adi: (3ø*(1(7ø. 2 Ders Kodu: BIO6410 3 4 5 6 7 8 9 10 11 12 13 14 Ders Türü: Seçmeli Ders Seviyesi Doktora 'HUVLQ9HULOGL÷L<ÕO 1 'HUVLQ9HULOGL÷L<DUÕ\ÕO 2 Dersin AKTS Kredisi: 5.00 Teorik Ders Saati (saat/Hafta) 3.00 Uygulama Ders Saati(saat/Hafta) 0.00 15 Laboratuvar Ders Saati (saat/hafta) : 0 'HUVLQgQNRúXOX 'HUVLQ|QúDUWÕ\RNWXU Dersin Dili: Türkçe 'HUVLQ9HULOLúùHNOL Yüz yüze Dersin Koordinatörü: Doç.Dr. FERDA ARI 'HUVL9HUHQ'L÷HUg÷UHWLP (OHPDQODUÕ 16 .RRUGLQDW|UøOHWLúLP%LOJLOHUL 17 Dersin WEB adresi: 18 'HUVLQ$PDFÕ 19 'HUVLQg÷UHQPH.D]DQÕPODUÕ 8/XGD÷hQLYHUVLWHVL)HQ(GHEL\DW)DNOWHVL%L\RORML%|OP16059 Nilüfer/BURSA Tlf: 0 224 294 1822 e-posta: ferdaoz@uludag.edu.tr '1$GL]LVLQGHGH÷LúLPOHUOHDoÕNODQDPD\DQJHQIRQNVL\RQX GH÷LúLNOLNOHULQLQWDQÕPODQPDVÕYHLOJLOLPHNDQL]PDODUÕQGHWD\OÕRODUDN WDUWÕúÕOPDVÕDPDoODQPDNWDGÕU 1 (SLJHQHWLNNDYUDPÕQÕDQOD\DELOPH 2 (SLJHQHWLNPHNDQL]PDODUÕPROHNOHUG]H\GH GH÷HUOHQGLUHELOPH 3 '1$PHWLODV\RQXYHHSLJHQHWLNDUDVÕQGDLOLúNL\L kavrayabilme 4 +LVWRQPRGLILNDV\RQODUÕYHHSLJHQHWLNDUDVÕQGDLOLúNL kurabilme 5 *HQUHJODV\RQXQGDHSLJHQHWLNPHNDQL]PDODUÕQUROQ anlama 6 (SLJHQHWLNNRQWUROND\EÕQÕQLQVDQODUGDQDVÕOKDVWDOÕNODUD QHGHQROGXNODUÕQÕDQDOL]HGHELOPH 7 (SLJHQHWLNGHIHNWOHUGHWHGDYL\DNODúÕPODUÕQÕNDYUD\DELOPH 8 9 10 20 'HUVLQøoHUL÷L Hafta '(56ød(5ø./(5ø Teorik 1 (SLJHQHWL÷HJLULú 2 DNA metilasyonu 3 DNA metiltransferazlar Uygulama 4 0HWLOED÷OD\DQSURWHLQOHUYHNURPDWLQOH LOLúNLOHUL 5 +LVWRQPRGLILNDV\RQODUÕYHHSLJHQHWLNJHQ UHJODV\RQODUÕ 6 +LVWRQPRGLILNDV\RQODUÕYHHSLJHQHWLNJHQ UHJODV\RQODUÕ 7 Epigenetik analiz yöntemleri 8 Epigenetik analiz yöntemleri 9 'HUVWHNUDUÕYH$UD6ÕQDY 10 *HOLúLPEL\RORMLVLQGHHSLJHQHWLNIDNW|UOHU 11 Kanser ve epigenetic ilaçlar 12 Kök hücre ve epigenetik 13 'L÷HURUJDQL]PDODUGDHSLJHQHWLN\DNODúÕPODU 14 Final 21 'HUV.LWDEÕ5HIHUDQVODUYHYH\D'L÷HU Kaynaklar: 22 Güncel makaleler Epigenetics [Paperback] C. David Allis (Author), Thomas Jenuwein (Author), Danny Reinberg (Author), Marie-Laure Caparros (Author) Publisher: Cold Spring Harbor Laboratory Press; 1st edition (October 31, 2007) Language: English ISBN-10: 0879698756 ISBN-13: 978-0879698751 'H÷HUOHQGLUPH <$5,<,/ødød$/,ù0$/$5, SAYISI .$7.,<h='(6ø $UD6ÕQDY .ÕVD6ÕQDY Ödev <ÕO6RQX6ÕQDYÕ Toplam <ÕOLoLoDOÕúPDODUÕQÕQ%DúDUÕ\D2UDQÕ )LQDOLQ%DúDUÕ\D2UDQÕ Toplam 1 30.00 0 0.00 1 20.00 1 50.00 3 100.00 23 $.76øù<h.h7$%/268 50.00 50.00 100.00 (7.ø1/ø. SAYISI Süresi (Saat) 7RSODPøú Yükü (Saat) Teorik Dersler 14 3.00 42.00 8\JXODPDOÕ'HUVOHU 0 0.00 0.00 6ÕQÕI'ÕúÕ'HUVdDOÕúPD6UHVLgQoDOÕúPD SHNLúWLUPH 14 4.00 56.00 Ödevler Projeler $UD]LdDOÕúPDODUÕ $UDVÕQDYODU 'L÷HU <DUÕ\ÕO6RQX6ÕQDYÕ 7RSODPøú<N 7RSODPøú<NVDDW Dersin AKTS Kredisi 1 28.00 28.00 1 20.00 20.00 0 0.00 0.00 1 3.00 3.00 7 4.00 28.00 1 3.00 3.00 180.00 6.00 5.00 352*5$0<(7(5/ø/ø./(5øø/( '(56gö5(7ø0.$=$1,0/$5,ø/øù.ø6ø7$%/268 25 PY1 PY2 PY3 PY4 PY5 PY6 PY7 PY8 PY9 PY10 PY11 PY12 PY13 PY14 PY15 PY16 ÖK1 5 5 4 4 2 4 4 3 4 5 4 0 0 0 0 0 ÖK2 4 4 4 3 2 4 4 3 3 4 4 0 0 0 0 0 ÖK3 4 4 4 3 3 4 4 3 3 4 4 0 0 0 0 0 ÖK4 4 4 4 3 3 4 4 3 3 4 4 0 0 0 0 0 ÖK5 3 4 4 3 3 4 4 3 3 4 4 0 0 0 0 0 ÖK6 4 5 4 3 3 4 4 3 4 4 5 0 0 0 0 0 ÖK7 4 5 4 3 3 4 4 3 4 4 5 0 0 0 0 0 g.g÷UHQPHND]DQÕPODU3<3URJUDP\HWHUOLOLNOHUL .DWNÕ Düzeyi: oRNGúN 'úN 3 Orta 4 Yüksek 5 Çok Yüksek